Genomic variants-driven drug repurposing for tuberculosis by utilizing the established bioinformatic-based approachShort communication Published on 2022-12-012022-10-05 Journal: Biochemistry and Biophysics Reports [Category] 신약개발, [키워드] annotations applied approach bioinformatics biological process CCR5 CD44 cellular component contribute CXCR4 demonstrated deregulation disease disease-associated drug Drug discovery Drug repurposing drug target evaluated Evidence facilitate functional functional annotation Genes genomic genomic variant genomic variants GWAS HLA-B identify implementation in-silico indication involved KEGG Missense mutation molecular overlapped Pathogenesis Pathway analysis provided risk SELP suggested target Treatment Tuberculosis variant [DOI] 10.1016/j.bbrep.2022.101334 [Article Type] Short communication
Multicenter Study on COVID-19 Lung Computed Tomography Segmentation with varying Glass Ground Opacities using Unseen Deep Learning Artificial Intelligence Paradigms: COVLIAS 1.0 Validation보이지 않는 딥 러닝 인공 지능 패러다임을 사용하여 다양한 유리 바닥 불투명도를 사용한 COVID-19 폐 컴퓨터 단층 촬영 분할에 대한 다기관 연구: COVLIAS 1.0 검증Multicenter Study Published on 2022-08-212022-09-12 Journal: Journal of medical systems [Category] 진단, [키워드] adjusted And AI annotations artificial automated automatically blinded clinical manifestations collected conducted consolidations COVID-19 CRO deep deep learning demonstrated GGO glass Glass ground opacities HDL Hounsfield units hybrid Hybrid deep learning hypotheses intelligence Italian learning lesion lung Lung CT multicenter multicenter study opacity Patient Performance metrics predict radiologist Regulatory Segmentation Solo deep learning. unit validation web-based system were used [DOI] 10.1007/s10916-022-01850-y PMC 바로가기 [Article Type] Multicenter Study
Lightweight Distributed Provenance Model for Complex Real–world Environments Research Published on 2022-08-172022-10-05 Journal: Scientific Data [Category] 진단, [키워드] acquisition annotations Clinical data Complete complex contribute dataset demonstrated Dependant domain Environment form histological information Lightweight Lineage Model organizations provenance reproducibility Research specimen [DOI] 10.1038/s41597-022-01537-6 [Article Type] Research
Continuous development of the semantic search engine preVIEW: from COVID-19 to long COVID의미 검색 엔진 preVIEW의 지속적인 개발: COVID-19에서 긴 COVID까지Article Published on 2022-07-012022-09-11 Journal: Database: The Journal of Biological Databases and [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added addition annotation annotations articles automatically Classifier Continuous coronavirus coronavirus disease COVID COVID-19 curated described disease False positives feature feedback include Infection MOST Occurrence participated peer-reviewed retrieved SARS-CoV-2 service severe acute respiratory syndrome Coronavirus Symptom true positive true positives Usability user variant virus [DOI] 10.1093/database/baac048 PMC 바로가기 [Article Type] Article
Integrating Domain Knowledge Into Deep Networks for Lung Ultrasound With Applications to COVID-19COVID-19에 응용 프로그램과 함께 폐 초음파를 위한 심층 네트워크에 도메인 지식 통합Article Published on 2022-03-012022-09-11 Journal: IEEE transactions on medical imaging [Category] SARS, 치료기술, [키워드] adopted anatomical annotations application consolidations COVID-19 COVID-19 severity dataset deep domain Efficacy evaluate evaluated feature Frame framework imaging modality knowledge lack linear Mask network Non-invasive Patient performed pixel predict probes promote required Safe Treatment Ultrasound [DOI] 10.1109/TMI.2021.3117246 PMC 바로가기 [Article Type] Article
The UCSC Genome Browser database: 2022 updateAcademicSubjects/SCI00010 Published on 2022-01-072022-10-31 Journal: Nucleic Acids Research [Category] COVID-19, SARS, [키워드] added annotations BLAT Clinical data datasets DECIPHER Features Genome genomic gnomAD highlight include Interpretation introduced Mutation new SARS-CoV-2 Organisms Other PCR Phylogenetic tree provide researcher SARS-CoV-2 track UCSC Genome Browser variant website [DOI] 10.1093/nar/gkab959 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
Automatic Segmentation of Novel Coronavirus Pneumonia Lesions in CT Images Utilizing Deep-Supervised Ensemble Learning NetworkMedicine Published on 2022-01-032022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] alleviate annotation annotations assist Automatic Coronavirus pneumonia COVID-19 COVID-19 lesion segmentation dataset deep learning deep-supervised ensemble learning network Diagnosis Effectiveness experiment Experimental result feature Image indicated intersection over union learning lesion living environment Local local and global features network novel coronavirus disease novel coronavirus pneumonia overcome overfitting Quantitative Segmentation Spread transfer transfer learning Treatment under CT imaging [DOI] 10.3389/fmed.2021.755309 PMC 바로가기 [Article Type] Medicine
3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomographyResearch Article Published on 2021-12-212022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] alteration Analysis analyzed annotations automated cardiac tissue concerning controls COVID-19 dataset deep learning distribution elevated High-resolution histopathological Histopathology Human Influenza Intussusceptive angiogenesis Laboratory measure Microscopy myocarditis Occurrence pathological pathological change Patient progression quantified Radiation Tensor tissue tomography Variation Vascular vessels virus X-ray X-ray tomography [DOI] 10.7554/eLife.71359 PMC 바로가기 [Article Type] Research Article
IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and EvolutionMedicine Published on 2021-12-132022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Analysis annotations association continuous monitoring coronavirus COVID-19 COVID-19 pandemic curated database detect effort ending functional Genetic Genetic variation Genome genomic variations help Interpretation knowledge lineages manuscript mechanisms monitoring Mutation provide public health Repository robust SARS-CoV-2 SARS-CoV-2 dynamics SARS-CoV-2 genome SARS-CoV-2 variation Surveillance variant variants Variation variations virus [DOI] 10.3389/fmed.2021.765249 PMC 바로가기 [Article Type] Medicine
Semi-Supervised Pipeline for Autonomous Annotation of SARS-CoV-2 GenomesSARS-COV-2 게놈의 자율 주석을위한 반 감독 파이프 라인Article Published on 2021-12-032022-09-10 Journal: Viruses [Category] SARS, 변종, [키워드] Accuracy analyzed annotation annotations Atypical automated autonomous average base bioinformatics characterized Cohort collected Computational biology conserved corpus COVID-19 D614G demonstrated described domain domains effort extensibility functional gene prediction Genome genome annotation Genome sequences genomic genomic sequencing Genomics Geography global pandemic greater high accuracy increase in Infection initial Intervention lab molecular target N501Y overcome polyprotein predicted Prokka Protein protein domain protein prediction protein sequence Proteins proteome public health Receptor binding domain reference genome replicase representing robustness SARS-CoV-2 SARS-CoV-2 genes SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-CoV-2 genomes scaled sequence sequence identity sequenced spike glycoprotein spike glycoprotein mutation transcriptional variant variants variants of concern [DOI] 10.3390/v13122426 PMC 바로가기 [Article Type] Article